Cryo-EM structure of the human parainfluenza virus hPIV3 L-P polymerase in dimeric form
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8kdb
Q-score: 0.577
Xie J, Ouizougun-Oubari M, Wang L, Zhai G, Wu D, Lin Z, Wang M, Ludeke B, Yan X, Nilsson T, Gao L, Huang X, Fearns R, Chen S
Nat Commun (2024) 15 pp. 3163-3163 [ DOI: doi:10.1038/s41467-024-47470-7 Pubmed: 38605025 ]
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase l (260 kDa, Protein from Human respirovirus 3)
- Magnesium ion (24 Da, Ligand)
- Human parainfluenza virus hpiv3 l-p polymerase in dimeric form (Complex from Human respirovirus 3)
- Phosphoprotein (68 kDa, Protein from Human respirovirus 3)
Cryo-EM structure of the human parainfluenza virus hPIV3 L-P polymerase in monomeric form
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8kdc
Q-score: 0.506
Xie J, Ouizougun-Oubari M, Wang L, Zhai G, Wu D, Lin Z, Wang M, Ludeke B, Yan X, Nilsson T, Gao L, Huang X, Fearns R, Chen S
Nat Commun (2024) 15 pp. 3163-3163 [ DOI: doi:10.1038/s41467-024-47470-7 Pubmed: 38605025 ]
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase l (260 kDa, Protein from Human respirovirus 3)
- Magnesium ion (24 Da, Ligand)
- Phosphoprotein (68 kDa, Protein from Human respirovirus 3)
- Human parainfluenza virus hpiv3 l-p polymerase in monomeric form (Complex from Human respirovirus 3)
Microtubule depolymerization contributes to spontaneous neurotransmitter release
Velasco CD, Santarella-Mellwig R, Schorb M, Gao L, Thorn-Seshold O, Llobet A
Commun Biol (2023) 6 [ DOI: 10.1038/s42003-023-04779-1 Pubmed: 37147475 ]
Image sets:
- dual-axis tilt series, Kif18A
- reconstructed and joined serial volumes, wild type
- dual-axis tilt series, wild type
- reconstructed and joined serial volumes, Kif18A
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 down RBD, state1)
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7e9n
Q-score: 0.31
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (124 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- Complex of the sars-cov-2 s-6p with 35b5 fab(1 down rbd, state1) (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with Fab30
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 7enf
Q-score: 0.485
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Complex of sars-cov-2 spike glycoprotein and fab30 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of fab30 (24 kDa, Protein from Homo sapiens)
- Fab30 (Complex)
- Heavy chain of fab30 (24 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 7eng
Q-score: 0.455
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Complex of sars-cov-2 spike glycoprotein and fab30 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of fab30 (24 kDa, Protein from Homo sapiens)
- Fab30 (Complex)
- Heavy chain of fab30 (24 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.69 Å
EM Method: Single-particle
Fitted PDBs: 7e9p
Q-score: 0.463
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- 35b5 fab (Complex)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Complex of sars-cov-2 spike glycoprotein and 35b5 fab (state2) (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Complex of sars-cov-2 spike glycoprotein and 35b5 fab (state1) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- 35b5 fab (Complex)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(3 up RBDs, state2)
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 7e9o
Q-score: 0.381
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- 35b5 fab (Complex)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Complex of sars-cov-2 spike glycoprotein and 35b5 fab (state2) (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 out RBD, state3)
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 7e9q
Q-score: 0.36
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L
Signal Transduct Target Ther (2022) 7 pp. 114- [ DOI: doi:10.1038/s41392-022-00954-8 ]
- Complex of sars-cov-2 spike glycoprotein and 35b5 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of 35b5 fab (23 kDa, Protein from Homo sapiens)
- Heavy chain of 35b5 fab (25 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike glycoprotein (Complex from Homo sapiens)
- 35b5 fab (Complex)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)